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Joint GWAS Analysis: Comparing similar GWAS at different genomic resolutions identifies novel pathway associations with six complex diseases

We show here that combining two existing genome wide association studies (GWAS) yields additional biologically relevant information, beyond that obtained by either GWAS separately. We propose Joint GWAS Analysis, a method that compares a pair of GWAS for similarity among the top SNP associations, to...

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Detalles Bibliográficos
Autores principales: McGeachie, Michael J., Clemmer, George L., Lasky-Su, Jessica, Dahlin, Amber, Raby, Benjamin A., Weiss, Scott T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378545/
https://www.ncbi.nlm.nih.gov/pubmed/25838990
http://dx.doi.org/10.1016/j.gdata.2014.04.004