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Sequencing methods and datasets to improve functional interpretation of sleeping beauty mutagenesis screens

BACKGROUND: Animal models of cancer are useful to generate complementary datasets for comparison to human tumor data. Insertional mutagenesis screens, such as those utilizing the Sleeping Beauty (SB) transposon system, provide a model that recapitulates the spontaneous development and progression of...

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Detalles Bibliográficos
Autores principales:	Riordan, Jesse D, Drury, Luke J, Smith, Ryan P, Brett, Benjamin T, Rogers, Laura M, Scheetz, Todd E, Dupuy, Adam J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378557/ https://www.ncbi.nlm.nih.gov/pubmed/25526783 http://dx.doi.org/10.1186/1471-2164-15-1150

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