Systemic Causes of Cholestasis

Systemic causes of cholestasis constitute a diverse group of diseases across organ systems. The pathophysiology of cholestasis in systemic disease can be a consequence of direct involvement of a disease process within the liver or extrahepatic biliary system or secondary to immune-mediated changes i...

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Detalles Bibliográficos
Autores principales: deLemos, Andrew S., Friedman, Lawrence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378837/
https://www.ncbi.nlm.nih.gov/pubmed/23540504
http://dx.doi.org/10.1016/j.cld.2012.11.001
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author deLemos, Andrew S.
Friedman, Lawrence S.
author_facet deLemos, Andrew S.
Friedman, Lawrence S.
author_sort deLemos, Andrew S.
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description Systemic causes of cholestasis constitute a diverse group of diseases across organ systems. The pathophysiology of cholestasis in systemic disease can be a consequence of direct involvement of a disease process within the liver or extrahepatic biliary system or secondary to immune-mediated changes in bile flow. Evaluating a patient with cholestasis for a systemic cause requires an understanding of the patient’s risk factors, clinical setting (eg, hospitalized or immunosuppressed patient), clinical features, and pattern of laboratory abnormalities.
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spelling pubmed-43788372015-03-30 Systemic Causes of Cholestasis deLemos, Andrew S. Friedman, Lawrence S. Clin Liver Dis Article Systemic causes of cholestasis constitute a diverse group of diseases across organ systems. The pathophysiology of cholestasis in systemic disease can be a consequence of direct involvement of a disease process within the liver or extrahepatic biliary system or secondary to immune-mediated changes in bile flow. Evaluating a patient with cholestasis for a systemic cause requires an understanding of the patient’s risk factors, clinical setting (eg, hospitalized or immunosuppressed patient), clinical features, and pattern of laboratory abnormalities. Elsevier Inc. 2013-05 2013-01-26 /pmc/articles/PMC4378837/ /pubmed/23540504 http://dx.doi.org/10.1016/j.cld.2012.11.001 Text en Copyright © 2013 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
deLemos, Andrew S.
Friedman, Lawrence S.
Systemic Causes of Cholestasis
title Systemic Causes of Cholestasis
title_full Systemic Causes of Cholestasis
title_fullStr Systemic Causes of Cholestasis
title_full_unstemmed Systemic Causes of Cholestasis
title_short Systemic Causes of Cholestasis
title_sort systemic causes of cholestasis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378837/
https://www.ncbi.nlm.nih.gov/pubmed/23540504
http://dx.doi.org/10.1016/j.cld.2012.11.001
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