Comparison of Newly Diagnosed and Relapsed Patients with Acute Promyelocytic Leukemia Treated with Arsenic Trioxide: Insight into Mechanisms of Resistance

There is limited data on the clinical, cellular and molecular changes in relapsed acute promyeloytic leukemia (RAPL) in comparison with newly diagnosed cases (NAPL). We undertook a prospective study to compare NAPL and RAPL patients treated with arsenic trioxide (ATO) based regimens. 98 NAPL and 28...

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Detalles Bibliográficos
Autores principales: Chendamarai, Ezhilarasi, Ganesan, Saravanan, Alex, Ansu Abu, Kamath, Vandana, Nair, Sukesh C., Nellickal, Arun Jose, Janet, Nancy Beryl, Srivastava, Vivi, Lakshmi, Kavitha M., Viswabandya, Auro, Abraham, Aby, Aiyaz, Mohammed, Mullapudi, Nandita, Mugasimangalam, Raja, Padua, Rose Ann, Chomienne, Christine, Chandy, Mammen, Srivastava, Alok, George, Biju, Balasubramanian, Poonkuzhali, Mathews, Vikram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378855/
https://www.ncbi.nlm.nih.gov/pubmed/25822503
http://dx.doi.org/10.1371/journal.pone.0121912

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