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Toll-like Receptor 4 Mediates the Inflammatory Responses and Matrix Protein Remodeling in Remote Non-Ischemic Myocardium in a Mouse Model of Myocardial Ischemia and Reperfusion
The signaling mechanism that mediates inflammatory responses in remote non-ischemic myocardium following regional ischemia/reperfusion (I/R) remains incompletely understood. Myocardial Toll-like receptor 4 (TLR4) can be activated by multiple proteins released from injured cells and plays a role in m...
Autores principales: | Zhai, Yufeng, Ao, Lihua, Cleveland, Joseph C., Zeng, Qingchun, Reece, T. Brett, Fullerton, David A., Meng, Xianzhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378913/ https://www.ncbi.nlm.nih.gov/pubmed/25823011 http://dx.doi.org/10.1371/journal.pone.0121853 |
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