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A System for Creating Stable Cell Lines that Express a Gene of Interest from a Bidirectional and Regulatable Herpes Simplex Virus Type 1 Promoter
Expression systems used to study the biological function of a gene of interest can have limited utility due to three major factors: i) weak or heterogeneous gene expression; ii) poorly controlled gene expression; and iii) low efficiencies of stable integration and persistent expression. We envisione...
Autores principales: | Chambers, Christopher B., Halford, William P., Geltz, Joshua, Villamizar, Olga, Gross, Jeffrey, Embalabala, Alison, Gershburg, Edward, Wilber, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378986/ https://www.ncbi.nlm.nih.gov/pubmed/25823013 http://dx.doi.org/10.1371/journal.pone.0122253 |
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