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Chemical and Thermal Unfolding of a Global Staphylococcal Virulence Regulator with a Flexible C-Terminal End

SarA, a Staphylococcus aureus-specific dimeric protein, modulates the expression of numerous proteins including various virulence factors. Interestingly, S. aureus synthesizes multiple SarA paralogs seemingly for optimizing the expression of its virulence factors. To understand the domain structure/...

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Detalles Bibliográficos
Autores principales: Mahapa, Avisek, Mandal, Sukhendu, Biswas, Anindya, Jana, Biswanath, Polley, Soumitra, Sau, Subrata, Sau, Keya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379015/
https://www.ncbi.nlm.nih.gov/pubmed/25822635
http://dx.doi.org/10.1371/journal.pone.0122168