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Pre-Existing Mutations in Reverse Transcriptase of Hepatitis B Virus in Treatment-Naive Chinese Patients with Chronic Hepatitis B

High rate of viral replication and lacking of proofreading activity in hepatitis B virus (HBV) polymerase lead to the generation of mutations in HBV virus. Mutations in the reverse transcriptase (RT) region of HBV polymerase are demonstrated to be strongly associated with drug resistance during anti...

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Detalles Bibliográficos
Autores principales:	Xu, Jie, Wu, Biao, Wang, Jing-Hui, Huang, Ling, Wang, Deng-yu, Zhao, Ling, Zhao, Guo-ping, Wang, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379075/ https://www.ncbi.nlm.nih.gov/pubmed/25821965 http://dx.doi.org/10.1371/journal.pone.0117429

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