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The Effect of Iron Ion on the Specificity of Photodynamic Therapy with 5-Aminolevulinic Acid

Recently, photodynamic therapy using 5-aminolevulinic acid (ALA-PDT) has been widely used in cancer therapy. ALA administration results in tumor-selective accumulation of the photosensitizer protoporphyrin IX (PpIX) via the heme biosynthetic pathway. Although ALA-PDT has selectivity for tumor cells,...

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Detalles Bibliográficos
Autores principales: Hayashi, Maiko, Fukuhara, Hideo, Inoue, Keiji, Shuin, Taro, Hagiya, Yuichiro, Nakajima, Motowo, Tanaka, Tohru, Ogura, Shun-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379089/
https://www.ncbi.nlm.nih.gov/pubmed/25822972
http://dx.doi.org/10.1371/journal.pone.0122351