Serum Levels of Caspase-Cleaved Cytokeratin-18 in Patients with Severe Traumatic Brain Injury Are Associated with Mortality: A Pilot Study

OBJECTIVE: There have been found apoptotic changes in brain tissue samples from animals and humans after a traumatic brain injury (TBI). The protein cytokeratin 18 (CK-18), present in epithelial cells, is cleaved by the action of caspases during apoptosis, and the resulting fragments are released in...

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Detalles Bibliográficos
Autores principales: Lorente, Leonardo, Martín, María M., González-Rivero, Agustín F., Argueso, Mónica, Ramos, Luis, Solé-Violán, Jordi, Cáceres, Juan J., Jiménez, Alejandro, Borreguero-León, Juan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379106/
https://www.ncbi.nlm.nih.gov/pubmed/25822281
http://dx.doi.org/10.1371/journal.pone.0121739

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