Cargando…

Secoisolariciresinol Diglucoside Abrogates Oxidative Stress-Induced Damage in Cardiac Iron Overload Condition

Cardiac iron overload is directly associated with cardiac dysfunction and can ultimately lead to heart failure. This study examined the effect of secoisolariciresinol diglucoside (SDG), a component of flaxseed, on iron overload induced cardiac damage by evaluating oxidative stress, inflammation and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Puukila, Stephanie, Bryan, Sean, Laakso, Anna, Abdel-Malak, Jessica, Gurney, Carli, Agostino, Adrian, Belló-Klein, Adriane, Prasad, Kailash, Khaper, Neelam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379144/ https://www.ncbi.nlm.nih.gov/pubmed/25822525 http://dx.doi.org/10.1371/journal.pone.0122852

Ejemplares similares

Potential protective properties of flax lignan secoisolariciresinol diglucoside
por: Imran, Muhammad, et al.
Publicado: (2015)

Secoisolariciresinol Diglucoside of Flaxseed and Its Metabolites: Biosynthesis and Potential for Nutraceuticals
por: Kezimana, Parfait, et al.
Publicado: (2018)

Identification and functional characterization of a flax UDP-glycosyltransferase glucosylating secoisolariciresinol (SECO) into secoisolariciresinol monoglucoside (SMG) and diglucoside (SDG)
por: Ghose, Kaushik, et al.
Publicado: (2014)

Secoisolariciresinol Diglucoside Improves Ovarian Reserve in Aging Mouse by Inhibiting Oxidative Stress
por: He, XueLai, et al.
Publicado: (2022)

Secoisolariciresinol diglucoside regulates estrogen receptor expression to ameliorate OVX-induced osteoporosis
por: Chen, Guofang, et al.
Publicado: (2023)

UGT74S1 is the key player in controlling secoisolariciresinol diglucoside (SDG) formation in flax
por: Fofana, Bourlaye, et al.
Publicado: (2017)

Flaxseed lignans enriched in secoisolariciresinol diglucoside prevent acute asbestos-induced peritoneal inflammation in mice
por: Pietrofesa, Ralph A., et al.
Publicado: (2016)

Secoisolariciresinol diglucoside is a blood-brain barrier protective and anti-inflammatory agent: implications for neuroinflammation
por: Rom, Slava, et al.
Publicado: (2018)

Secoisolariciresinol diglucoside induces pyroptosis by activating caspase‐1 to cleave GSDMD in colorectal cancer cells
por: Chen, Tuo, et al.
Publicado: (2022)

Secoisolariciresinol diglucoside and anethole ameliorate lipid abnormalities, oxidative injury, hypercholesterolemia, heart, and liver conditions
por: Noreen, Sana, et al.
Publicado: (2023)

The Synthetic Lignan Secoisolariciresinol Diglucoside Prevents Asbestos-Induced NLRP3 Inflammasome Activation in Murine Macrophages
por: Pietrofesa, Ralph A., et al.
Publicado: (2017)

Synthetic Secoisolariciresinol Diglucoside (LGM2605) Protects Human Lung in an Ex Vivo Model of Proton Radiation Damage
por: Velalopoulou, Anastasia, et al.
Publicado: (2017)

Synthetic Secoisolariciresinol Diglucoside Attenuates Established Pain, Oxidative Stress and Neuroinflammation in a Rodent Model of Painful Radiculopathy
por: Kartha, Sonia, et al.
Publicado: (2020)

The Flaxseed-Derived Lignan Phenolic Secoisolariciresinol Diglucoside (SDG) Protects Non-Malignant Lung Cells from Radiation Damage
por: Velalopoulou, Anastasia, et al.
Publicado: (2015)

Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605) Reduces Asbestos-Induced Cytotoxicity in an Nrf2-Dependent and -Independent Manner
por: Pietrofesa, Ralph A., et al.
Publicado: (2018)

Synthetic Secoisolariciresinol Diglucoside (LGM2605) Prevents Asbestos-Induced Inflammation and Genotoxic Cell Damage in Human Mesothelial Cells
por: Pietrofesa, Ralph A., et al.
Publicado: (2022)

The flaxseed lignan secoisolariciresinol diglucoside decreases local inflammation, suppresses NFκB signaling, and inhibits mammary tumor growth
por: Bowers, Laura W., et al.
Publicado: (2018)

Induced Mutagenesis in UGT74S1 Gene Leads to Stable New Flax Lines with Altered Secoisolariciresinol Diglucoside (SDG) Profiles
por: Fofana, Bourlaye, et al.
Publicado: (2017)

Secoisolariciresinol Diglucoside Delays the Progression of Aging-Related Diseases and Extends the Lifespan of Caenorhabditis elegans via DAF-16 and HSF-1
por: Lu, Min, et al.
Publicado: (2020)

Copper Oxide Nanoparticle-Induced Acute Inflammatory Response and Injury in Murine Lung Is Ameliorated by Synthetic Secoisolariciresinol Diglucoside (LGM2605)
por: Pietrofesa, Ralph A., et al.
Publicado: (2021)

Laser Microdissection and Spatiotemporal Pinoresinol-Lariciresinol Reductase Gene Expression Assign the Cell Layer-Specific Accumulation of Secoisolariciresinol Diglucoside in Flaxseed Coats
por: Fang, Jingjing, et al.
Publicado: (2016)

Data on cecal and fecal microbiota and predicted metagenomes profiles of female mice receiving whole flaxseed or its oil and secoisolariciresinol diglucoside components
por: Taibi, Amel, et al.
Publicado: (2021)

Role of L-type Ca2+ channels in iron transport and iron-overload cardiomyopathy
por: Oudit, Gavin Y., et al.
Publicado: (2006)

Asbestos Induces Oxidative Stress and Activation of Nrf2 Signaling in Murine Macrophages: Chemopreventive Role of the Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605)
por: Pietrofesa, Ralph A., et al.
Publicado: (2016)

Cookies enriched with anethole and secoisolariciresinol diglucoside from flaxseed and fennel seeds improve hypercholesterolemia, lipid profile, and liver functions: A pilot study
por: Noreen, Sana, et al.
Publicado: (2023)

Gamma-irradiation produces active chlorine species (ACS) in physiological solutions: Secoisolariciresinol diglucoside (SDG) scavenges ACS - A novel mechanism of DNA radioprotection
por: Mishra, Om P., et al.
Publicado: (2016)

Ionic Liquid-Based Ultrasonic-Assisted Extraction of Secoisolariciresinol Diglucoside from Flaxseed (Linum usitatissimum L.) with Further Purification by an Aqueous Two-Phase System
por: Tan, Zhi-Jian, et al.
Publicado: (2015)

Water Stress and Seed Color Interacting to Impact Seed and Oil Yield, Protein, Mucilage, and Secoisolariciresinol Diglucoside Content in Cultivated Flax (Linum usitatissimum L.)
por: Zare, Sara, et al.
Publicado: (2023)

Linagliptin and secoisolariciresinol diglucoside attenuate hyperlipidemia and cardiac hypertrophy induced by a high-methionine diet in rats via suppression of hyperhomocysteinemia-induced endoplasmic reticulum stress
por: Jalal, Israa A., et al.
Publicado: (2023)

Data on mammary gland microRNAs expression, their predicted gene targets and corresponding pathway analysis in female mice receiving flaxseed or its oil and secoisolariciresinol diglucoside components
por: Wu, Diana, et al.
Publicado: (2022)

Dietary Iron Overload Abrogates Chemically-Induced Liver Cirrhosis in Rats
por: Atarashi, Machi, et al.
Publicado: (2018)

Secoisolariciresinol Diglucoside Exerts Anti-Inflammatory and Antiapoptotic Effects through Inhibiting the Akt/IκB/NF-κB Pathway on Human Umbilical Vein Endothelial Cells
por: Zhang, Shaoyang, et al.
Publicado: (2020)

Oxidative Stress and Antioxidant Strategies in Cardiovascular Disease
por: Belló-Klein, Adriane, et al.
Publicado: (2014)

The cardioprotective effects of secoisolariciresinol diglucoside (flaxseed lignan) against cafeteria diet-induced cardiac fibrosis and vascular injury in rats: an insight into apelin/AMPK/FOXO3a signaling pathways
por: Abdelwahab, Azza H., et al.
Publicado: (2023)

Efficacy of a Low Dose of Estrogen on Antioxidant Defenses and Heart Rate Variability
por: Campos, Cristina, et al.
Publicado: (2014)

Negative-Pressure Cavitation Extraction of Secoisolariciresinol Diglycoside from Flaxseed Cakes
por: Tian, Hao, et al.
Publicado: (2015)

Iron overload disorders
por: Hsu, Christine C., et al.
Publicado: (2022)

Iron Chelators in Treatment of Iron Overload
por: Entezari, Sarina, et al.
Publicado: (2022)

Bucindolol Modulates Cardiac Remodeling by Attenuating Oxidative Stress in H9c2 Cardiac Cells Exposed to Norepinephrine
por: de Lima-Seolin, Bruna Gazzi, et al.
Publicado: (2019)

Kraft Process—Formation of Secoisolariciresinol Structures and Incorporation of Fatty Acids in Kraft Lignin
por: Lahtinen, Maarit H., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6vn057r51p8bot6k85n1tt3hi2