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A 3D computer-assisted treatment planning system for breast cancer brachytherapy treatment
PURPOSE: Brachytherapy is an option for treatment of breast cancer in some cases. This modality requires patient-specific dosimetry based on CT simulator scans. A 3D computer-assisted breast brachytherapy treatment planning system called Vision was developed and tested. METHODS: The brachytherapy tr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379415/ https://www.ncbi.nlm.nih.gov/pubmed/25001868 http://dx.doi.org/10.1007/s11548-014-1092-y |
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author | Jiang, Yuchong Rachel Sykes, Edward R. |
author_facet | Jiang, Yuchong Rachel Sykes, Edward R. |
author_sort | Jiang, Yuchong Rachel |
collection | PubMed |
description | PURPOSE: Brachytherapy is an option for treatment of breast cancer in some cases. This modality requires patient-specific dosimetry based on CT simulator scans. A 3D computer-assisted breast brachytherapy treatment planning system called Vision was developed and tested. METHODS: The brachytherapy treatment planning system used volume estimation and dose analysis with advanced 3D visualization. The patient treatment volume reconstruction was designed to ensure high-volume accuracy requirement of radioactive seed implantation procedure for this treatment. The system enables interactive placement of radioactive seeds embedded in original patient CT images with 3D display. RESULTS: The system achieved 99.73 % accuracy in volume estimation measured against the true volume and is statistically significantly more accurate than current existing commercial software at the [Formula: see text] level. CONCLUSION: A virtual 3D environment was developed to perform volume measurements, seed placements, and dose distribution planning and analysis based on 2D contours on patient CT images. This system was demonstrated to be feasible and accurate in a clinical setting. |
format | Online Article Text |
id | pubmed-4379415 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-43794152015-04-07 A 3D computer-assisted treatment planning system for breast cancer brachytherapy treatment Jiang, Yuchong Rachel Sykes, Edward R. Int J Comput Assist Radiol Surg Original Article PURPOSE: Brachytherapy is an option for treatment of breast cancer in some cases. This modality requires patient-specific dosimetry based on CT simulator scans. A 3D computer-assisted breast brachytherapy treatment planning system called Vision was developed and tested. METHODS: The brachytherapy treatment planning system used volume estimation and dose analysis with advanced 3D visualization. The patient treatment volume reconstruction was designed to ensure high-volume accuracy requirement of radioactive seed implantation procedure for this treatment. The system enables interactive placement of radioactive seeds embedded in original patient CT images with 3D display. RESULTS: The system achieved 99.73 % accuracy in volume estimation measured against the true volume and is statistically significantly more accurate than current existing commercial software at the [Formula: see text] level. CONCLUSION: A virtual 3D environment was developed to perform volume measurements, seed placements, and dose distribution planning and analysis based on 2D contours on patient CT images. This system was demonstrated to be feasible and accurate in a clinical setting. Springer Berlin Heidelberg 2014-07-08 2015 /pmc/articles/PMC4379415/ /pubmed/25001868 http://dx.doi.org/10.1007/s11548-014-1092-y Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Original Article Jiang, Yuchong Rachel Sykes, Edward R. A 3D computer-assisted treatment planning system for breast cancer brachytherapy treatment |
title | A 3D computer-assisted treatment planning system for breast cancer brachytherapy treatment |
title_full | A 3D computer-assisted treatment planning system for breast cancer brachytherapy treatment |
title_fullStr | A 3D computer-assisted treatment planning system for breast cancer brachytherapy treatment |
title_full_unstemmed | A 3D computer-assisted treatment planning system for breast cancer brachytherapy treatment |
title_short | A 3D computer-assisted treatment planning system for breast cancer brachytherapy treatment |
title_sort | 3d computer-assisted treatment planning system for breast cancer brachytherapy treatment |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379415/ https://www.ncbi.nlm.nih.gov/pubmed/25001868 http://dx.doi.org/10.1007/s11548-014-1092-y |
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