HPV-E7 Delivered by Engineered Exosomes Elicits a Protective CD8(+) T Cell-Mediated Immune Response

We developed an innovative strategy to induce a cytotoxic T cell (CTL) immune response against protein antigens of choice. It relies on the production of exosomes, i.e., nanovesicles spontaneously released by all cell types. We engineered the upload of huge amounts of protein antigens upon fusion wi...

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Detalles Bibliográficos
Autores principales: Di Bonito, Paola, Ridolfi, Barbara, Columba-Cabezas, Sandra, Giovannelli, Andrea, Chiozzini, Chiara, Manfredi, Francesco, Anticoli, Simona, Arenaccio, Claudia, Federico, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379561/
https://www.ncbi.nlm.nih.gov/pubmed/25760140
http://dx.doi.org/10.3390/v7031079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379561/
https://www.ncbi.nlm.nih.gov/pubmed/25760140
http://dx.doi.org/10.3390/v7031079

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