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HPV-E7 Delivered by Engineered Exosomes Elicits a Protective CD8(+) T Cell-Mediated Immune Response
We developed an innovative strategy to induce a cytotoxic T cell (CTL) immune response against protein antigens of choice. It relies on the production of exosomes, i.e., nanovesicles spontaneously released by all cell types. We engineered the upload of huge amounts of protein antigens upon fusion wi...
Autores principales: | Di Bonito, Paola, Ridolfi, Barbara, Columba-Cabezas, Sandra, Giovannelli, Andrea, Chiozzini, Chiara, Manfredi, Francesco, Anticoli, Simona, Arenaccio, Claudia, Federico, Maurizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379561/ https://www.ncbi.nlm.nih.gov/pubmed/25760140 http://dx.doi.org/10.3390/v7031079 |
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