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Both ERK1 and ERK2 Are Required for Enterovirus 71 (EV71) Efficient Replication

It has been demonstrated that MEK1, one of the two MEK isoforms in Raf-MEK-ERK1/2 pathway, is essential for successful EV71 propagation. However, the distinct function of ERK1 and ERK2 isoforms, the downstream kinases of MEKs, remains unclear in EV71 replication. In this study, specific ERK siRNAs a...

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Detalles Bibliográficos
Autores principales:	Zhu, Meng, Duan, Hao, Gao, Meng, Zhang, Hao, Peng, Yihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379574/ https://www.ncbi.nlm.nih.gov/pubmed/25803100 http://dx.doi.org/10.3390/v7031344

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