Splenic and lymph nodal involvement in sarcoidosis mimicking lymphoma on fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography

Sarcoidosis is a multisystemic disease presenting with well-defined, bilateral, symmetric hilar and right paratracheal lymph node enlargement. Recently, fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) has been used to stage and detect occult site of...

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Detalles Bibliográficos
Autores principales: Jung, Rayamajhi Sampanna, Mittal, Bhagwant Rai, Maturu, Nagarjuna Venkata, Bal, Amanjit, Bhattacharya, Anish, Gupta, Dheeraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Case Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379672/
https://www.ncbi.nlm.nih.gov/pubmed/25829731
http://dx.doi.org/10.4103/0972-3919.152975
Descripción
Sumario:Sarcoidosis is a multisystemic disease presenting with well-defined, bilateral, symmetric hilar and right paratracheal lymph node enlargement. Recently, fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) has been used to stage and detect occult site of active inflammation in sarcoidosis. F-18 FDG PET/CT has become a cornerstone imaging modality in the modern lymphoma management, which can present with generalized lymphadenopathy including mediastinal. We present a case series, which shows how sarcoidosis can be a “great mimic of lymphoma” on F-18 FDG PET/CT and how histopathology is essential in diagnosing sarcoidosis and ruling out lymphoma.

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