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Human pluripotent stem cell derived midbrain PITX3(eGFP/w) neurons: a versatile tool for pharmacological screening and neurodegenerative modeling

PITX3 expression is confined to adult midbrain dopaminergic (mDA) neurons. In this study we describe the generation and basic functional characteristics of mDA neurons derived from a human pluripotent stem cell (hPSC) line expressing eGFP under the control of the PITX3 promoter. Flow cytometry showe...

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Detalles Bibliográficos
Autores principales:	Watmuff, Bradley, Hartley, Brigham J., Hunt, Cameron P. J., Fabb, Stewart A., Pouton, Colin W., Haynes, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379917/ https://www.ncbi.nlm.nih.gov/pubmed/25873861 http://dx.doi.org/10.3389/fncel.2015.00104

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