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Long-term culture and significant expansion of human Sertoli cells whilst maintaining stable global phenotype and AKT and SMAD1/5 activation

BACKGROUND: Sertoli cells play key roles in regulating spermatogenesis and testis development by providing structural and nutritional supports. Recent studies demonstrate that Sertoli cells can be converted into functional neural stem cells. Adult Sertoli cells have previously been considered the te...

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Detalles Bibliográficos
Autores principales: Guo, Ying, Hai, Yanan, Yao, Chencheng, Chen, Zheng, Hou, Jingmei, Li, Zheng, He, Zuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380114/
https://www.ncbi.nlm.nih.gov/pubmed/25880873
http://dx.doi.org/10.1186/s12964-015-0101-2