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Long-term culture and significant expansion of human Sertoli cells whilst maintaining stable global phenotype and AKT and SMAD1/5 activation
BACKGROUND: Sertoli cells play key roles in regulating spermatogenesis and testis development by providing structural and nutritional supports. Recent studies demonstrate that Sertoli cells can be converted into functional neural stem cells. Adult Sertoli cells have previously been considered the te...
Autores principales: | Guo, Ying, Hai, Yanan, Yao, Chencheng, Chen, Zheng, Hou, Jingmei, Li, Zheng, He, Zuping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380114/ https://www.ncbi.nlm.nih.gov/pubmed/25880873 http://dx.doi.org/10.1186/s12964-015-0101-2 |
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