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Apparent lack of physical or functional interaction between Ca(V)1.1 and its distal C terminus

Ca(V)1.1 acts as both the voltage sensor that triggers excitation–contraction coupling in skeletal muscle and as an L-type Ca(2+) channel. It has been proposed that, after its posttranslational cleavage, the distal C terminus of Ca(V)1.1 remains noncovalently associated with proximal Ca(V)1.1, and t...

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Detalles Bibliográficos
Autores principales: Ohrtman, Joshua D., Romberg, Christin F., Moua, Ong, Bannister, Roger A., Levinson, S. Rock, Beam, Kurt G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380213/
https://www.ncbi.nlm.nih.gov/pubmed/25779869
http://dx.doi.org/10.1085/jgp.201411292