Enteric Neuron Imbalance and Proximal Dysmotility in Ganglionated Intestine of the Sox10(Dom/+) Hirschsprung Mouse Model

BACKGROUND & AIMS: In Hirschsprung disease (HSCR), neural crest-derived progenitors (NCPs) fail to completely colonize the intestine so that the enteric nervous system is absent from distal bowel. Despite removal of the aganglionic region, many HSCR patients suffer from residual intestinal dysmo...

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Detalles Bibliográficos
Autores principales: Musser, Melissa A., Correa, Hernan, Southard-Smith, E. Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380251/
https://www.ncbi.nlm.nih.gov/pubmed/25844395
http://dx.doi.org/10.1016/j.jcmgh.2014.08.002

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