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Decreased Chloride Channel Expression in the Dorsolateral Prefrontal Cortex in Schizophrenia

Alterations in GABAergic neurotransmission are implicated in several psychiatric illnesses, including schizophrenia. The Na-K-Cl and K-Cl cotransporters regulate intracellular chloride levels. Abnormalities in cotransporter expression levels could shift the chloride electrochemical gradient and impa...

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Detalles Bibliográficos
Autores principales: Sullivan, Courtney R., Funk, Adam J., Shan, Dan, Haroutunian, Vahram, McCullumsmith, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380350/
https://www.ncbi.nlm.nih.gov/pubmed/25826365
http://dx.doi.org/10.1371/journal.pone.0123158