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Network Analyses Reveal Novel Aspects of ALS Pathogenesis

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by selective loss of motor neurons, muscle atrophy and paralysis. Mutations in the human VAMP-associated protein B (hVAPB) cause a heterogeneous group of motor neuron diseases including ALS8. Despite extensive res...

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Detalles Bibliográficos
Autores principales: Sanhueza, Mario, Chai, Andrea, Smith, Colin, McCray, Brett A., Simpson, T. Ian, Taylor, J. Paul, Pennetta, Giuseppa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380362/
https://www.ncbi.nlm.nih.gov/pubmed/25826266
http://dx.doi.org/10.1371/journal.pgen.1005107