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Facile Supermolecular Aptamer Inhibitors of L-Selectin
Multivalent interactions occur frequently in nature, where they mediate high-affinity interactions between cells, proteins, or molecules. Here, we report on a method to generate multivalent aptamers (Multi-Aptamers) that target L-selectin function using rolling circle amplification (RCA). We find th...
Autores principales: | Chang, Elizabeth K., Eckert, Mark A., Ali, M. Monsur, Riazifar, Hamidreza, Pone, Egest J., Liu, Linan, Zhao, Weian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380364/ https://www.ncbi.nlm.nih.gov/pubmed/25826688 http://dx.doi.org/10.1371/journal.pone.0123034 |
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