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Facile Supermolecular Aptamer Inhibitors of L-Selectin

Multivalent interactions occur frequently in nature, where they mediate high-affinity interactions between cells, proteins, or molecules. Here, we report on a method to generate multivalent aptamers (Multi-Aptamers) that target L-selectin function using rolling circle amplification (RCA). We find th...

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Detalles Bibliográficos
Autores principales: Chang, Elizabeth K., Eckert, Mark A., Ali, M. Monsur, Riazifar, Hamidreza, Pone, Egest J., Liu, Linan, Zhao, Weian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380364/
https://www.ncbi.nlm.nih.gov/pubmed/25826688
http://dx.doi.org/10.1371/journal.pone.0123034

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