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Impact of Leishmania Infection on Host Macrophage Nuclear Physiology and Nucleopore Complex Integrity

The protease GP63 is an important virulence factor of Leishmania parasites. We previously showed that GP63 reaches the perinuclear area of host macrophages and that it directly modifies nuclear translocation of the transcription factors NF-κB and AP-1. Here we describe for the first time, using mole...

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Detalles Bibliográficos
Autores principales:	Isnard, Amandine, Christian, Jan G., Kodiha, Mohamed, Stochaj, Ursula, McMaster, W. Robert, Olivier, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380401/ https://www.ncbi.nlm.nih.gov/pubmed/25826301 http://dx.doi.org/10.1371/journal.ppat.1004776

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