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Integration of Shallow Gradients of Shh and Netrin-1 Guides Commissural Axons
During nervous system development, gradients of Sonic Hedgehog (Shh) and Netrin-1 attract growth cones of commissural axons toward the floor plate of the embryonic spinal cord. Mice defective for either Shh or Netrin-1 signaling have commissural axon guidance defects, suggesting that both Shh and Ne...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380419/ https://www.ncbi.nlm.nih.gov/pubmed/25826604 http://dx.doi.org/10.1371/journal.pbio.1002119 |