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Pre-Exposure to Ionizing Radiation Stimulates DNA Double Strand Break End Resection, Promoting the Use of Homologous Recombination Repair

The choice of DNA double strand break (DSB) repair pathway is determined at the stage of DSB end resection. Resection was proposed to control the balance between the two major DSB repair pathways, homologous recombination (HR) and non-homologous end joining (NHEJ). Here, we examined the regulation o...

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Detalles Bibliográficos
Autores principales: Nakajima, Nakako Izumi, Hagiwara, Yoshihiko, Oike, Takahiro, Okayasu, Ryuichi, Murakami, Takeshi, Nakano, Takashi, Shibata, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380452/
https://www.ncbi.nlm.nih.gov/pubmed/25826455
http://dx.doi.org/10.1371/journal.pone.0122582

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