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Methylation-Sensitive Expression of a DNA Demethylase Gene Serves As an Epigenetic Rheostat

Genomes must balance active suppression of transposable elements (TEs) with the need to maintain gene expression. In Arabidopsis, euchromatic TEs are targeted by RNA-directed DNA methylation (RdDM). Conversely, active DNA demethylation prevents accumulation of methylation at genes proximal to these...

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Detalles Bibliográficos
Autores principales: Williams, Ben P., Pignatta, Daniela, Henikoff, Steven, Gehring, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380477/
https://www.ncbi.nlm.nih.gov/pubmed/25826366
http://dx.doi.org/10.1371/journal.pgen.1005142

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