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Under-Utilization of Implantable Cardioverter Defibrillators in Patients with Heart Failure - The Current State of Sudden Cardiac Death Prophylaxis

BACKGROUND: Despite ACC/AHA guidelines indicating implantable cardioverter defibrillator (ICD) as class I therapy for primary prevention of sudden cardiac death in patients with EF≤35%, ICD utilization rates in real world practice have been low. OBJECTIVE: To determine the rate of ICD implantation a...

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Autores principales: Pillarisetti, Jayasree, Emert, Martin, Biria, Mazda, Chotia, Rashaad, Guda, Rajeshwer, Bommana, Sudharani, Pimentel, Rhea, Vacek, James, Dendi, Raghuveer, Berenbom, Loren, Dawn, Buddhadeb, Lakkireddy, Dhanunjaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380691/
https://www.ncbi.nlm.nih.gov/pubmed/25852239
http://dx.doi.org/10.1016/S0972-6292(16)30838-5
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author Pillarisetti, Jayasree
Emert, Martin
Biria, Mazda
Chotia, Rashaad
Guda, Rajeshwer
Bommana, Sudharani
Pimentel, Rhea
Vacek, James
Dendi, Raghuveer
Berenbom, Loren
Dawn, Buddhadeb
Lakkireddy, Dhanunjaya
author_facet Pillarisetti, Jayasree
Emert, Martin
Biria, Mazda
Chotia, Rashaad
Guda, Rajeshwer
Bommana, Sudharani
Pimentel, Rhea
Vacek, James
Dendi, Raghuveer
Berenbom, Loren
Dawn, Buddhadeb
Lakkireddy, Dhanunjaya
author_sort Pillarisetti, Jayasree
collection PubMed
description BACKGROUND: Despite ACC/AHA guidelines indicating implantable cardioverter defibrillator (ICD) as class I therapy for primary prevention of sudden cardiac death in patients with EF≤35%, ICD utilization rates in real world practice have been low. OBJECTIVE: To determine the rate of ICD implantation at a tertiary care academic center and to assess the reasons for under-utilization of the same. METHODS: Review of a prospectively collected database which included all patients diagnosed with an EF≤35% was performed to assess the rate of ICD implantation and mortality. Reasons for non-implantation of ICD were then assessed from detailed chart review. RESULTS: A total of 707 patients (age 69.4 ± 14.1 years) with mean EF of 26±7% were analyzed. Only 28% (200/707) of patients had ICDs implanted. Mortality was lower in the group with ICD (25% vs 37%, p=0.004). When patients who either died or were lost to follow-up prior to 2005 were excluded, ICD utilization rate was still low at 37.6%. The most common reason for non-implantation of ICD was physicians not discussing this option with their patients. Patient refusal was the second most common reason. CONCLUSIONS: ICD Implantation rates for primary prevention of SCD in patients with EF≤35% is low. Physician and patient education should be addressed to improve the utilization rates.
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spelling pubmed-43806912015-04-07 Under-Utilization of Implantable Cardioverter Defibrillators in Patients with Heart Failure - The Current State of Sudden Cardiac Death Prophylaxis Pillarisetti, Jayasree Emert, Martin Biria, Mazda Chotia, Rashaad Guda, Rajeshwer Bommana, Sudharani Pimentel, Rhea Vacek, James Dendi, Raghuveer Berenbom, Loren Dawn, Buddhadeb Lakkireddy, Dhanunjaya Indian Pacing Electrophysiol J Original Article BACKGROUND: Despite ACC/AHA guidelines indicating implantable cardioverter defibrillator (ICD) as class I therapy for primary prevention of sudden cardiac death in patients with EF≤35%, ICD utilization rates in real world practice have been low. OBJECTIVE: To determine the rate of ICD implantation at a tertiary care academic center and to assess the reasons for under-utilization of the same. METHODS: Review of a prospectively collected database which included all patients diagnosed with an EF≤35% was performed to assess the rate of ICD implantation and mortality. Reasons for non-implantation of ICD were then assessed from detailed chart review. RESULTS: A total of 707 patients (age 69.4 ± 14.1 years) with mean EF of 26±7% were analyzed. Only 28% (200/707) of patients had ICDs implanted. Mortality was lower in the group with ICD (25% vs 37%, p=0.004). When patients who either died or were lost to follow-up prior to 2005 were excluded, ICD utilization rate was still low at 37.6%. The most common reason for non-implantation of ICD was physicians not discussing this option with their patients. Patient refusal was the second most common reason. CONCLUSIONS: ICD Implantation rates for primary prevention of SCD in patients with EF≤35% is low. Physician and patient education should be addressed to improve the utilization rates. Elsevier 2016-04-26 /pmc/articles/PMC4380691/ /pubmed/25852239 http://dx.doi.org/10.1016/S0972-6292(16)30838-5 Text en © 2015 Indian Heart Rhythm Society. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Pillarisetti, Jayasree
Emert, Martin
Biria, Mazda
Chotia, Rashaad
Guda, Rajeshwer
Bommana, Sudharani
Pimentel, Rhea
Vacek, James
Dendi, Raghuveer
Berenbom, Loren
Dawn, Buddhadeb
Lakkireddy, Dhanunjaya
Under-Utilization of Implantable Cardioverter Defibrillators in Patients with Heart Failure - The Current State of Sudden Cardiac Death Prophylaxis
title Under-Utilization of Implantable Cardioverter Defibrillators in Patients with Heart Failure - The Current State of Sudden Cardiac Death Prophylaxis
title_full Under-Utilization of Implantable Cardioverter Defibrillators in Patients with Heart Failure - The Current State of Sudden Cardiac Death Prophylaxis
title_fullStr Under-Utilization of Implantable Cardioverter Defibrillators in Patients with Heart Failure - The Current State of Sudden Cardiac Death Prophylaxis
title_full_unstemmed Under-Utilization of Implantable Cardioverter Defibrillators in Patients with Heart Failure - The Current State of Sudden Cardiac Death Prophylaxis
title_short Under-Utilization of Implantable Cardioverter Defibrillators in Patients with Heart Failure - The Current State of Sudden Cardiac Death Prophylaxis
title_sort under-utilization of implantable cardioverter defibrillators in patients with heart failure - the current state of sudden cardiac death prophylaxis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380691/
https://www.ncbi.nlm.nih.gov/pubmed/25852239
http://dx.doi.org/10.1016/S0972-6292(16)30838-5
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