The Necessity of Having a Tetradentate Ligand to Extract Copper(II) Ions from Amyloids

The accumulation of redox-active metal ions, in particular copper, in amyloid plaques is considered to the cause of the intensive oxidation damage to the brain of patients with Alzheimers disease (AD). Drug candidates based on a bis(8-aminoquinoline) tetradentate ligand are able to efficiently extra...

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Detalles Bibliográficos
Autores principales: Nguyen, Michel, Rechignat, Lionel, Robert, Anne, Meunier, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380950/
https://www.ncbi.nlm.nih.gov/pubmed/25861567
http://dx.doi.org/10.1002/open.201402075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380950/
https://www.ncbi.nlm.nih.gov/pubmed/25861567
http://dx.doi.org/10.1002/open.201402075

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