PIK3CA mutations predict recurrence in localized microsatellite stable colon cancer

PIK3CA, which encodes the p110α catalytic subunit of PI3Kα, is one of the most frequently altered oncogenes in colon cancer (CC), but its prognostic value is still a matter of debate. Few reports have addressed the association between PIK3CA mutations and survival and their results are controversial...

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Detalles Bibliográficos
Autores principales: Manceau, Gilles, Marisa, Laetitia, Boige, Valérie, Duval, Alex, Gaub, Marie-Pierre, Milano, Gérard, Selves, Janick, Olschwang, Sylviane, Jooste, Valérie, le Legrain, Michè, Lecorre, Delphine, Guenot, Dominique, Etienne-Grimaldi, Marie-Christine, Kirzin, Sylvain, Martin, Laurent, Lepage, Come, Bouvier, Anne-Marie, Laurent-Puig, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380963/
https://www.ncbi.nlm.nih.gov/pubmed/25641861
http://dx.doi.org/10.1002/cam4.370

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