Aberrant DNA hypermethylation reduces the expression of the desmosome-related molecule periplakin in esophageal squamous cell carcinoma

Periplakin (PPL), a member of the plakin family of proteins that localizes to desmosomes and intermediate filaments, is downregulated in human esophageal squamous cell carcinoma (ESCC). Little is known, however, about the molecular mechanism underlying the regulation of PPL expression and the contri...

Descripción completa

Detalles Bibliográficos
Autores principales: Otsubo, Takeshi, Hagiwara, Teruki, Tamura-Nakano, Miwa, Sezaki, Takuhito, Miyake, Oki, Hinohara, Chihaya, Shimizu, Toshio, Yamada, Kazuhiko, Dohi, Taeko, Kawamura, Yuki I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380967/
https://www.ncbi.nlm.nih.gov/pubmed/25583674
http://dx.doi.org/10.1002/cam4.369

Ejemplares similares

Ejemplares similares