Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex

The yeast KEOPS protein complex comprising Kae1, Bud32, Cgi121, Pcc1 and Gon7 is responsible for the essential tRNA threonylcarbamoyladenosine (t(6)A) modification. Deletion of genes coding for the KEOPS subunits also affects telomere elongation and transcriptional regulation. In the present work, t...

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Detalles Bibliográficos
Autores principales: Zhang, Wenhua, Collinet, Bruno, Graille, Marc, Daugeron, Marie-Claire, Lazar, Noureddine, Libri, Domenico, Durand, Dominique, van Tilbeurgh, Herman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381065/
https://www.ncbi.nlm.nih.gov/pubmed/25735745
http://dx.doi.org/10.1093/nar/gkv155

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