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Genome-wide CIITA-binding profile identifies sequence preferences that dictate function versus recruitment

The class II transactivator (CIITA) is essential for the expression of major histocompatibility complex class II (MHC-II) genes; however, the role of CIITA in gene regulation outside of MHC-II biology is not fully understood. To comprehensively map CIITA-bound loci, ChIP-seq was performed in the hum...

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Detalles Bibliográficos
Autores principales:	Scharer, Christopher D., Choi, Nancy M., Barwick, Benjamin G., Majumder, Parimal, Lohsen, Sarah, Boss, Jeremy M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381081/ https://www.ncbi.nlm.nih.gov/pubmed/25753668 http://dx.doi.org/10.1093/nar/gkv182

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