Trade-offs between tRNA abundance and mRNA secondary structure support smoothing of translation elongation rate

Translation of protein from mRNA is a complex multi-step process that occurs at a non-uniform rate. Variability in ribosome speed along an mRNA enables refinement of the proteome and plays a critical role in protein biogenesis. Detailed single protein studies have found both tRNA abundance and mRNA...

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Detalles Bibliográficos
Autores principales: Gorochowski, Thomas E., Ignatova, Zoya, Bovenberg, Roel A.L., Roubos, Johannes A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381083/
https://www.ncbi.nlm.nih.gov/pubmed/25765653
http://dx.doi.org/10.1093/nar/gkv199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381083/
https://www.ncbi.nlm.nih.gov/pubmed/25765653
http://dx.doi.org/10.1093/nar/gkv199

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