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Trade-offs between tRNA abundance and mRNA secondary structure support smoothing of translation elongation rate
Translation of protein from mRNA is a complex multi-step process that occurs at a non-uniform rate. Variability in ribosome speed along an mRNA enables refinement of the proteome and plays a critical role in protein biogenesis. Detailed single protein studies have found both tRNA abundance and mRNA...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381083/ https://www.ncbi.nlm.nih.gov/pubmed/25765653 http://dx.doi.org/10.1093/nar/gkv199 |