Cargando…

Direct PCR: a new pharmacogenetic approach for the inexpensive testing of HLA-B*57:01

One of the most successful applications of pharmacogenetics research is the genetic screening for HLA-B*57:01, strongly associated with an increased risk to develop hypersensitivity reaction in HIV-positive patients following abacavir administration. Taking into consideration the limits of current g...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cascella, R, Strafella, C, Ragazzo, M, Zampatti, S, Borgiani, P, Gambardella, S, Pirazzoli, A, Novelli, G, Giardina, E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381103/ https://www.ncbi.nlm.nih.gov/pubmed/25201286 http://dx.doi.org/10.1038/tpj.2014.48

Ejemplares similares

The Pharmacogenomic HLA Biomarker Associated to Adverse Abacavir Reactions: Comparative Analysis of Different Genotyping Methods
por: Stocchi, Laura, et al.
Publicado: (2012)

Precision Medicine into Clinical Practice: A Web-Based Tool Enables Real-Time Pharmacogenetic Assessment of Tailored Treatments in Psychiatric Disorders
por: Zampatti, Stefania, et al.
Publicado: (2021)

Genetic Counselling Improves the Molecular Characterisation of Dementing Disorders
por: Zampatti, Stefania, et al.
Publicado: (2021)

Analysis of ACE2 Genetic Variability among Populations Highlights a Possible Link with COVID-19-Related Neurological Complications
por: Strafella, Claudia, et al.
Publicado: (2020)

Age-Related Macular Degeneration: Insights into Inflammatory Genes
por: Cascella, Raffaella, et al.
Publicado: (2014)

The Genetics and the Genomics of Primary Congenital Glaucoma
por: Cascella, Raffaella, et al.
Publicado: (2015)

Genetic Variants Allegedly Linked to Antisocial Behaviour Are Equally Distributed Across Different Populations
por: Zampatti, Stefania, et al.
Publicado: (2021)

Investigation of Genetic Variations of IL6 and IL6R as Potential Prognostic and Pharmacogenetics Biomarkers: Implications for COVID-19 and Neuroinflammatory Disorders
por: Strafella, Claudia, et al.
Publicado: (2020)

Comparative Analysis of Real-Time Polymerase Chain Reaction Methods to Typing HLA-B*57:01 in HIV-1-Positive Patients
por: Falasca, Francesca, et al.
Publicado: (2016)

Haplotypes in IL-8 Gene Are Associated to Age-Related Macular Degeneration: A Case-Control Study
por: Ricci, Federico, et al.
Publicado: (2013)

Correction: Haplotypes in IL-8 Gene Are Associated to Age-Related Macular Degeneration: A Case-Control Study
por: Ricci, Federico, et al.
Publicado: (2013)

Application of Precision Medicine in Neurodegenerative Diseases
por: Strafella, Claudia, et al.
Publicado: (2018)

HLA-B*57:01 allele prevalence in HIV-infected North American subjects and the impact of allele testing on the incidence of abacavir-associated hypersensitivity reaction in HLA-B*57:01-negative subjects
por: Small, Catherine Butkus, et al.
Publicado: (2017)

NGS Analysis for Molecular Diagnosis of Retinitis Pigmentosa (RP): Detection of a Novel Variant in PRPH2 Gene
por: Strafella, Claudia, et al.
Publicado: (2019)

A Pharmacogenetics Study in Mozambican Patients Treated with Nevirapine: Full Resequencing of TRAF3IP2 Gene Shows a Novel Association with SJS/TEN Susceptibility
por: Ciccacci, Cinzia, et al.
Publicado: (2015)

Uncovering genetic and non-genetic biomarkers specific for exudative age-related macular degeneration: significant association of twelve variants
por: Cascella, Raffaella, et al.
Publicado: (2017)

KIF3A and IL-4 are disease-specific biomarkers for psoriatic arthritis susceptibility
por: Cascella, Raffaella, et al.
Publicado: (2017)

Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1
por: O'Connor, Geraldine M., et al.
Publicado: (2015)

Alterations in the HLA-B*57:01 Immunopeptidome by Flucloxacillin and Immunogenicity of Drug-Haptenated Peptides
por: Puig, Montserrat, et al.
Publicado: (2021)

Genetic Counseling and NGS Screening for Recessive LGMD2A Families
por: Strafella, Claudia, et al.
Publicado: (2020)

RNAseq-Based Prioritization Revealed COL6A5, COL8A1, COL10A1 and MIR146A as Common and Differential Susceptibility Biomarkers for Psoriasis and Psoriatic Arthritis: Confirmation from Genotyping Analysis of 1417 Italian Subjects
por: Caputo, Valerio, et al.
Publicado: (2020)

Pharmacogenomics: An Update on Biologics and Small-Molecule Drugs in the Treatment of Psoriasis
por: Caputo, Valerio, et al.
Publicado: (2021)

Improving turnaround times for HLA-B*27 and HLA-B*57:01 gene testing: a Barts Health NHS Trust quality improvement project
por: White, Emma, et al.
Publicado: (2021)

A Splicing Variant in RDH8 Is Associated with Autosomal Recessive Stargardt Macular Dystrophy
por: Zampatti, Stefania, et al.
Publicado: (2023)

Influence of Glycosylation Inhibition on the Binding of KIR3DL1 to HLA-B*57:01
por: Salzberger, Wilhelm, et al.
Publicado: (2015)

Unravelling the Proteomics of HLA-B*57:01(+) Antigen Presenting Cells during Abacavir Medication
por: Haukamp, Funmilola Josephine, et al.
Publicado: (2022)

Whole genome amplification and real-time PCR in forensic casework
por: Giardina, Emiliano, et al.
Publicado: (2009)

HLA-E*01:01 + HLA-E*01:01 genotype confers less susceptibility to COVID-19, while HLA-E*01:03 + HLA-E*01:03 genotype is associated with more severe disease
por: Hosseini, Ehteramolsadat, et al.
Publicado: (2023)

C9orf72-Related Neurodegenerative Diseases: From Clinical Diagnosis to Therapeutic Strategies
por: Zampatti, Stefania, et al.
Publicado: (2022)

WARE: Wet AMD Risk-Evaluation Tool as a Clinical Decision-Support System Integrating Genetic and Non-Genetic Factors
por: Fabrizio, Carlo, et al.
Publicado: (2022)

Acyclovir Has Low but Detectable Influence on HLA-B*57:01 Specificity without Inducing Hypersensitivity
por: Metushi, Imir G., et al.
Publicado: (2015)

HLA-B*57:01 allele prevalence in treatment-Naïve HIV-infected patients from Colombia
por: Martínez Buitrago, Ernesto, et al.
Publicado: (2019)

Prevalence of human leukocyte antigen HLA-B*57:01 in individuals with HIV in West and Central Africa
por: Kolou, Malewe, et al.
Publicado: (2021)

CCM no. 80-01: no. 57
Publicado: (1980)

The Interplay between miRNA-Related Variants and Age-Related Macular Degeneration: EVIDENCE of Association of MIR146A and MIR27A
por: Strafella, Claudia, et al.
Publicado: (2019)

Impact of HLA-B*58:01 allele and allopurinol-induced cutaneous adverse drug reactions: evidence from 21 pharmacogenetic studies
por: Wu, Ran, et al.
Publicado: (2016)

Comparison of Methods for In-House Screening of HLA-B*57:01 to Prevent Abacavir Hypersensitivity in HIV-1 Care
por: De Spiegelaere, Ward, et al.
Publicado: (2015)

Adverse drug reactions triggered by the common HLA-B*57:01 variant: a molecular docking study
por: Van Den Driessche, George, et al.
Publicado: (2017)

Validation of a Rapid, Robust, Inexpensive Screening Method for Detecting the HLA-B(*)58:01 Allele in the Prevention of Allopurinol-Induced Severe Cutaneous Adverse Reactions
por: Nguyen, Dinh Van, et al.
Publicado: (2017)

Shared (epi)genomic background connecting neurodegenerative diseases and type 2 diabetes
por: Caputo, Valerio, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0p7nb1ih44vaj00iqta7guf5nk