Oncostatin M Modulation of Lipid Storage

Oncostatin M (OSM) is a cytokine belonging to the gp130 family, whose members serve pleiotropic functions. However, several actions of OSM are unique from those of other gp130 cytokines, and these actions may have critical roles in inflammatory mechanisms influencing several metabolic and biological...

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Detalles Bibliográficos
Autores principales: Elks, Carrie M., Stephens, Jacqueline M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381222/
https://www.ncbi.nlm.nih.gov/pubmed/25689119
http://dx.doi.org/10.3390/biology4010151
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author Elks, Carrie M.
Stephens, Jacqueline M.
author_facet Elks, Carrie M.
Stephens, Jacqueline M.
author_sort Elks, Carrie M.
collection PubMed
description Oncostatin M (OSM) is a cytokine belonging to the gp130 family, whose members serve pleiotropic functions. However, several actions of OSM are unique from those of other gp130 cytokines, and these actions may have critical roles in inflammatory mechanisms influencing several metabolic and biological functions of insulin-sensitive tissues. In this review, the actions of OSM in adipose tissue and liver are discussed, with an emphasis on lipid metabolism.
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spelling pubmed-43812222015-05-04 Oncostatin M Modulation of Lipid Storage Elks, Carrie M. Stephens, Jacqueline M. Biology (Basel) Review Oncostatin M (OSM) is a cytokine belonging to the gp130 family, whose members serve pleiotropic functions. However, several actions of OSM are unique from those of other gp130 cytokines, and these actions may have critical roles in inflammatory mechanisms influencing several metabolic and biological functions of insulin-sensitive tissues. In this review, the actions of OSM in adipose tissue and liver are discussed, with an emphasis on lipid metabolism. MDPI 2015-02-13 /pmc/articles/PMC4381222/ /pubmed/25689119 http://dx.doi.org/10.3390/biology4010151 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Elks, Carrie M.
Stephens, Jacqueline M.
Oncostatin M Modulation of Lipid Storage
title Oncostatin M Modulation of Lipid Storage
title_full Oncostatin M Modulation of Lipid Storage
title_fullStr Oncostatin M Modulation of Lipid Storage
title_full_unstemmed Oncostatin M Modulation of Lipid Storage
title_short Oncostatin M Modulation of Lipid Storage
title_sort oncostatin m modulation of lipid storage
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381222/
https://www.ncbi.nlm.nih.gov/pubmed/25689119
http://dx.doi.org/10.3390/biology4010151
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