Identification of a novel selective agonist of PPARγ with no promotion of adipogenesis and less inhibition of osteoblastogenesis

Nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) plays an important role in the regulation of glucose homeostasis and lipid metabolism. However, current PPARγ-targeting drugs such as thiazolidinediones (TZDs) are associated with undesirable side effects. We identified a small mo...

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Detalles Bibliográficos
Autores principales: Liu, Chang, Feng, Tingting, Zhu, Ningyu, Liu, Peng, Han, Xiaowan, Chen, Minghua, Wang, Xiao, Li, Ni, Li, Yongzhen, Xu, Yanni, Si, Shuyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381330/
https://www.ncbi.nlm.nih.gov/pubmed/25827822
http://dx.doi.org/10.1038/srep09530

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