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Downregulation of Wnt signaling by sonic hedgehog activation promotes repopulation of human tumor cell lines
Tumor repopulation after radiotherapy is a big obstacle for clinical cancer therapy. The molecular mechanisms of tumor cell repopulation after radiotherapy remain unclear. This study investigated the role of sonic hedgehog (SHH) and Wnt signaling pathways in tumor repopulation after radiotherapy in...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381337/ https://www.ncbi.nlm.nih.gov/pubmed/25713298 http://dx.doi.org/10.1242/dmm.018887 |