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Reduced Slc2a4/GLUT4 expression in subcutaneous adipose tissue of monosodium glutamate obese mice is recovered after atorvastatin treatment

BACKGROUND: Decreased expression of glucose transporter protein GLUT4, encoded by the solute carrier 2A4 (Slc2a4) gene, is involved in obesity-induced insulin resistance. Local tissue inflammation, by nuclear factor-κB (NFκB)-mediated pathway, has been related to Slc2a4 repression; a mechanism that...

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Detalles Bibliográficos
Autores principales: Poletto, Ana Cláudia, David-Silva, Aline, Yamamoto, Aline Pedro de Melo, Machado, Ubiratan Fabres, Furuya, Daniela Tomie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381373/
https://www.ncbi.nlm.nih.gov/pubmed/25834641
http://dx.doi.org/10.1186/s13098-015-0015-6

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