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Reduced Slc2a4/GLUT4 expression in subcutaneous adipose tissue of monosodium glutamate obese mice is recovered after atorvastatin treatment
BACKGROUND: Decreased expression of glucose transporter protein GLUT4, encoded by the solute carrier 2A4 (Slc2a4) gene, is involved in obesity-induced insulin resistance. Local tissue inflammation, by nuclear factor-κB (NFκB)-mediated pathway, has been related to Slc2a4 repression; a mechanism that...
Autores principales: | Poletto, Ana Cláudia, David-Silva, Aline, Yamamoto, Aline Pedro de Melo, Machado, Ubiratan Fabres, Furuya, Daniela Tomie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381373/ https://www.ncbi.nlm.nih.gov/pubmed/25834641 http://dx.doi.org/10.1186/s13098-015-0015-6 |
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