Sequencing, identification and mapping of primed L1 elements (SIMPLE) reveals significant variation in full length L1 elements between individuals

BACKGROUND: There are over a half a million copies of L1 retroelements in the human genome which are responsible for as much as 0.5% of new human genetic diseases. Most new L1 inserts arise from young source elements that are polymorphic in the human genome. Highly active polymorphic “hot” L1 source...

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Detalles Bibliográficos
Autores principales: Streva, Vincent A, Jordan, Vallmer E, Linker, Sara, Hedges, Dale J, Batzer, Mark A, Deininger, Prescott L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381410/
https://www.ncbi.nlm.nih.gov/pubmed/25887476
http://dx.doi.org/10.1186/s12864-015-1374-y

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