Cargando…

Mouse mammary stem cells express prognostic markers for triple-negative breast cancer

INTRODUCTION: Triple-negative breast cancer (TNBC) is a heterogeneous group of tumours in which chemotherapy, the current mainstay of systemic treatment, is often initially beneficial but with a high risk of relapse and metastasis. There is currently no means of predicting which TNBC will relapse. W...

Descripción completa

Detalles Bibliográficos
Autores principales:	Soady, Kelly J, Kendrick, Howard, Gao, Qiong, Tutt, Andrew, Zvelebil, Marketa, Ordonez, Liliana D, Quist, Jelmar, Tan, David Wei-Min, Isacke, Clare M, Grigoriadis, Anita, Smalley, Matthew J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381533/ https://www.ncbi.nlm.nih.gov/pubmed/25849541 http://dx.doi.org/10.1186/s13058-015-0539-6

Ejemplares similares

Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate
por: Kendrick, Howard, et al.
Publicado: (2008)

Embryonic mammary signature subsets are activated in Brca1(-/- )and basal-like breast cancers
por: Zvelebil, Marketa, et al.
Publicado: (2013)

Slugging their way to immortality: driving mammary epithelial cells into a stem cell-like state
por: Soady, Kelly, et al.
Publicado: (2012)

Transcriptome analysis of embryonic mammary cells reveals insights into mammary lineage establishment
por: Wansbury, Olivia, et al.
Publicado: (2011)

CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells
por: Sleeman, Katherine E, et al.
Publicado: (2006)

Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland
por: Sleeman, Katherine E., et al.
Publicado: (2007)

NOTCH and AKT Signalling Interact to Drive Mammary Tumour Heterogeneity
por: Ordonez, Liliana, et al.
Publicado: (2023)

Random Forest Modelling of High-Dimensional Mixed-Type Data for Breast Cancer Classification
por: Quist, Jelmar, et al.
Publicado: (2021)

Systemic immune reaction in axillary lymph nodes adds to tumor-infiltrating lymphocytes in triple-negative breast cancer prognostication
por: Liu, Fangfang, et al.
Publicado: (2021)

Integrated Multimodal Analyses of DNA Damage Response and Immune Markers as Predictors of Response in Metastatic Triple-Negative Breast Cancer in the TNT Trial (NCT00532727)
por: Tovey, Holly, et al.
Publicado: (2023)

Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B
por: Akre, Monica K., et al.
Publicado: (2016)

Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer
por: Patel, Nirmesh, et al.
Publicado: (2018)

Pan-cancer transcriptomic analysis dissects immune and proliferative functions of APOBEC3 cytidine deaminases
por: Ng, Joseph C F, et al.
Publicado: (2019)

CDK Inhibition Primes for Anti-PD-L1 Treatment in Triple-Negative Breast Cancer Models
por: Cheung, Anthony, et al.
Publicado: (2022)

Molecular characterisation of cell line models for triple-negative breast cancers
por: Grigoriadis, Anita, et al.
Publicado: (2012)

Annexin A8 Identifies a Subpopulation of Transiently Quiescent c-Kit Positive Luminal Progenitor Cells of the Ductal Mammary Epithelium
por: Iglesias, Juan Manuel, et al.
Publicado: (2015)

Genomic distance entrained clustering and regression modelling highlights interacting genomic regions contributing to proliferation in breast cancer
por: Dexter, Tim J, et al.
Publicado: (2010)

Assessment of structural chromosomal instability phenotypes as biomarkers of carboplatin response in triple negative breast cancer: the TNT trial
por: Sipos, O., et al.
Publicado: (2021)

Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes in Triple-Negative Breast Cancer
por: Harris, Robert J., et al.
Publicado: (2021)

Regulator of G-protein signalling 2 mRNA is differentially expressed in mammary epithelial subpopulations and over-expressed in the majority of breast cancers
por: Smalley, Matthew J, et al.
Publicado: (2007)

Controversial issues in the neoadjuvant treatment of triple-negative breast cancer
por: Fitzpatrick, Amanda, et al.
Publicado: (2019)

Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium
por: Daly, C S, et al.
Publicado: (2017)

Identification of differentially expressed sense and antisense transcript pairs in breast epithelial tissues
por: Grigoriadis, Anita, et al.
Publicado: (2009)

Pregnancy in the mature adult mouse does not alter the proportion of mammary epithelial stem/progenitor cells
por: Britt, Kara L, et al.
Publicado: (2009)

Comparative gene expression study highlights molecular similarities between triple negative breast cancer tumours and feline mammary carcinomas
por: Sommerville, Lara, et al.
Publicado: (2022)

Integrated genomic analysis of triple-negative breast cancers reveals novel microRNAs associated with clinical and molecular phenotypes and sheds light on the pathways they control
por: de Rinaldis, Emanuele, et al.
Publicado: (2013)

Generation and characterisation of two D2A1 mammary cancer sublines to model spontaneous and experimental metastasis in a syngeneic BALB/c host
por: Jungwirth, Ute, et al.
Publicado: (2018)

FLIGHT: database and tools for the integration and cross-correlation of large-scale RNAi phenotypic datasets
por: Sims, David, et al.
Publicado: (2006)

pSTIING: a ‘systems’ approach towards integrating signalling pathways, interaction and transcriptional regulatory networks in inflammation and cancer
por: Ng, Aylwin, et al.
Publicado: (2006)

Reproductive history determines Erbb2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model
por: Ordonez, Liliana D., et al.
Publicado: (2021)

Adipose-enriched peri-tumoral stroma, in contrast to myofibroblast-enriched stroma, prognosticates poorer survival in breast cancers
por: Lau, Hannah Si Hui, et al.
Publicado: (2023)

Who do they think they are? Wnt-responsive cells reveal their family trees
por: Ordonez, Liliana, et al.
Publicado: (2012)

Antitumor activity of new chemical compounds in triple negative mammary adenocarcinoma models
por: Giolito, María V, et al.
Publicado: (2020)

LMD-18. Detection and serial monitoring of CSF ctDNA in breast cancer leptomeningeal disease (BCLM)
por: Fitzpatrick, Amanda, et al.
Publicado: (2021)

Expression of LGR5 in mammary myoepithelial cells and in triple-negative breast cancers
por: Lee, Hyun Ju, et al.
Publicado: (2021)

Mammary adipocytes protect triple-negative breast cancer cells from ferroptosis
por: Xie, Yizhao, et al.
Publicado: (2022)

Highway to heaven: mammary gland development and differentiation
por: Melchor, Lorenzo, et al.
Publicado: (2008)

Are triple-negative tumours and basal-like breast cancer synonymous?
por: Rakha, Emad A, et al.
Publicado: (2007)

Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids
por: Jardé, Thierry, et al.
Publicado: (2016)

Activation of mammalian target of rapamycin (mTOR) in triple negative feline mammary carcinomas
por: Maniscalco, Lorella, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_jodkuef4gc6o0pcago2a1ucch9