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Hypoxia-inducible factor 1 alpha is regulated by RBM38, a RNA-binding protein and a p53 family target, via mRNA translation

Hypoxia-inducible factor 1 (HIF1), a heterodimeric transcription factor, consists of HIF1α and HIF1β and is necessary for cell growth and survival under a hypoxic condition. Thus, the level and activity of HIF1α needs to be tightly controlled. Indeed, HIF1α protein stability is controlled by prolyl...

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Detalles Bibliográficos
Autores principales:	Cho, Seong-Jun, Teng, I-Fang, Zhang, Min, Yin, Tiffany, Jung, Yong-Sam, Zhang, Jin, Chen, Xinbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381596/ https://www.ncbi.nlm.nih.gov/pubmed/25622105

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