Irinotecan treatment and senescence failure promote the emergence of more transformed and invasive cells that depend on anti-apoptotic Mcl-1

Induction of senescence by chemotherapy was initially characterized as a suppressive response that prevents tumor cell proliferation. However, in response to treatment, it is not really known how cells can survive senescence and how irreversible this pathway is. In this study, we analyzed cell escap...

Descripción completa

Detalles Bibliográficos
Autores principales: Jonchère, Barbara, Vétillard, Alexandra, Toutain, Bertrand, Lam, David, Bernard, Anne Charlotte, Henry, Cécile, Trécesson, Sophie De Carné, Gamelin, Erick, Juin, Philippe, Guette, Catherine, Coqueret, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381604/
https://www.ncbi.nlm.nih.gov/pubmed/25565667

Ejemplares similares

Ejemplares similares