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Mechanism of enhanced antiosteoporosis effect of circinal–icaritin by self-assembled nanomicelles in vivo with suet oil and sodium deoxycholate

BACKGROUND: Circinal–icaritin (CIT), one new active aglycone of Epimedium, can exert a beneficial effect on osteoporotic bone. However, its low bioavailability limits its clinical efficacy for the treatment of osteoporosis. MATERIALS AND METHODS: In this paper, suet oil (SO) was used to improve the...

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Detalles Bibliográficos
Autores principales: Jiang, Jun, Li, Jie, Zhang, Zhenhai, Sun, E, Feng, Liang, Jia, Xiaobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381633/
https://www.ncbi.nlm.nih.gov/pubmed/25848257
http://dx.doi.org/10.2147/IJN.S76191