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TR4 nuclear receptor enhances prostate cancer initiation via altering the stem cell population and EMT signals in the PPARG-deleted prostate cells

A recent report indicated that the TR4 nuclear receptor might suppress the prostate cancer (PCa) initiation via modulating the DNA damage/repair system. Knocking-out peroxisome proliferator-activated receptor gamma (PPARG), a nuclear receptor that shares similar ligands/activators with TR4, promoted...

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Detalles Bibliográficos
Autores principales: Lin, Shin-Jen, Yang, Dong-Rong, Wang, Nancy, Jiang, Ming, Miyamoto, Hiroshi, Li, Gonghui, Chang, Chawnshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381707/
https://www.ncbi.nlm.nih.gov/pubmed/25859557