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Landscape of DNA methylation on the X chromosome reflects CpG density, functional chromatin state and X-chromosome inactivation

X-chromosome inactivation (XCI) achieves dosage compensation between males and females through the silencing of the majority of genes on one of the female X chromosomes. Thus, the female X chromosomes provide a unique opportunity to study euchromatin and heterochromatin of allelic regions within the...

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Detalles Bibliográficos
Autores principales: Cotton, Allison M., Price, E. Magda, Jones, Meaghan J., Balaton, Bradley P., Kobor, Michael S., Brown, Carolyn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381753/
https://www.ncbi.nlm.nih.gov/pubmed/25381334
http://dx.doi.org/10.1093/hmg/ddu564