Cargando…

Polysulfated Trehalose as a Novel Anticoagulant Agent with Dual Mode of Action

Physiological hemostatic balance is a coordinated outcome of counteracting coagulation and fibrinolytic systems. An imbalance of procoagulant and anticoagulant factors may result in life threatening thromboembolism. Presently, anticoagulant administration is the first line of therapy for the treatme...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rashid, Qudsia, Abid, Mohammad, Gupta, Neha, Tyagi, Tarun, Ashraf, Mohammad Z., Jairajpuri, Mohamad Aman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381846/ https://www.ncbi.nlm.nih.gov/pubmed/25866798 http://dx.doi.org/10.1155/2015/630482

Ejemplares similares

Elucidating the specificity of non-heparin-based conformational activators of antithrombin for factor Xa inhibition
por: Rashid, Qudsia, et al.
Publicado: (2014)

Deciphering the role of trehalose in hindering antithrombin polymerization
por: Naseem, Asma, et al.
Publicado: (2019)

Serpin Inhibition Mechanism: A Delicate Balance between Native Metastable State and Polymerization
por: Khan, Mohammad Sazzad, et al.
Publicado: (2011)

Antithrombin III Deficiency in Indian Patients with Deep Vein Thrombosis: Identification of First India Based AT Variants Including a Novel Point Mutation (T280A) that Leads to Aggregation
por: Bhakuni, Teena, et al.
Publicado: (2015)

Potential Anti-SARS-CoV-2 Activity of Pentosan Polysulfate and Mucopolysaccharide Polysulfate
por: Zhang, Fuming, et al.
Publicado: (2022)

Maculopathy caused by pentosan polysulfate
por: Rosenberg, Daniel, et al.
Publicado: (2021)

Pentosan Polysulfate: A Novel Therapy for the Mucopolysaccharidoses
por: Schuchman, Edward H., et al.
Publicado: (2013)

Visual Function in Pentosan Polysulfate Sodium Maculopathy
por: Lyons, Riley J., et al.
Publicado: (2020)

Effects of pentosan polysulfate and polysulfated glycosaminoglycan on chondrogenesis of canine bone marrow-derived mesenchymal stem cells in alginate and micromass culture
por: BWALYA, Eugene C., et al.
Publicado: (2017)

Mechanisms Involved in the Anti-Inflammatory Action of a Polysulfated Fraction from Gracilaria cornea in Rats
por: Coura, Chistiane Oliveira, et al.
Publicado: (2015)

Broad Th2 neutralization and anti‐inflammatory action of pentosan polysulfate sodium in experimental allergic rhinitis
por: Sanden, Caroline, et al.
Publicado: (2017)

Maculopathie causée par le polysulfate de pentosan
por: Rosenberg, Daniel, et al.
Publicado: (2021)

Pentosan polysulfate regulates hepcidin expression in native Mongolian horses
por: WIJEKOON, Suranji, et al.
Publicado: (2022)

Pentosan Polysulfate Affords Pleotropic Protection to Multiple Cells and Tissues
por: Smith, Margaret M., et al.
Publicado: (2023)

Strand 6B deformation and residues exposure towards N-terminal end of helix B during proteinase inhibition by Serpins
por: Singh, Poonam, et al.
Publicado: (2011)

Using serpins cysteine protease cross-specificity to possibly trap SARS-CoV-2 Mpro with reactive center loop chimera
por: Jairajpuri, Mohamad Aman, et al.
Publicado: (2020)

A case of pentosan polysulfate maculopathy originally diagnosed as stargardt disease
por: Vora, Robin A., et al.
Publicado: (2020)

Maculopathy Secondary to Pentosan Polysulfate Use: A Single-Center Experience
por: Kalbag, Neil S, et al.
Publicado: (2021)

Type 3 macular neovascularization in a patient with pentosan polysulfate maculopathy
por: Bousquet, Elodie, et al.
Publicado: (2022)

A hydrophobic patch surrounding Trp154 in human neuroserpin controls the helix F dynamics with implications in inhibition and aggregation
por: Ali, Mohammad Farhan, et al.
Publicado: (2017)

Pentosan Polysulfate: Oral Versus Subcutaneous Injection in Mucopolysaccharidosis Type I Dogs
por: Simonaro, Calogera M., et al.
Publicado: (2016)

Safety Study of Sodium Pentosan Polysulfate for Adult Patients with Mucopolysaccharidosis Type II
por: Orii, Kenji, et al.
Publicado: (2019)

Acute and severe haemorrhage following pentosan polysulfate injection in a Cornish Rex
por: Tong, Miranda X, et al.
Publicado: (2021)

Polysulfates Block SARS‐CoV‐2 Uptake through Electrostatic Interactions
por: Nie, Chuanxiong, et al.
Publicado: (2021)

Pentosan Polysulfate Sodium-Associated Pigmentary Retinopathy: Risk Factors and Fundus Findings
por: Leung, Ella H, et al.
Publicado: (2021)

Efficacy of Pentosan Polysulfate Treatment in Patients with Interstitial Cystitis/Bladder Pain Syndrome
por: Arıkan, Mehmet Gürkan, et al.
Publicado: (2023)

Dual mode of action of metformin on mitochondrial metabolism
por: Andrzejewski, Sylvia, et al.
Publicado: (2014)

Redox Specificity of 2-Hydroxyacid-Coupled NAD(+)/NADH Dehydrogenases: A Study Exploiting “Reactive” Arginine as a Reporter of Protein Electrostatics
por: Gupta, Pooja, et al.
Publicado: (2013)

Correction: Redox Specificity of 2-Hydroxyacid-Coupled NAD(+)/NADH Dehydrogenases: A Study Exploiting "Reactive" Arginine as a Reporter of Protein Electrostatics
por: Gupta, Pooja, et al.
Publicado: (2016)

A Novel Trehalose Synthase for the Production of Trehalose and Trehalulose
por: Agarwal, Neera, et al.
Publicado: (2021)

Anti-inflammatory actions of Pentosan polysulfate sodium in a mouse model of influenza virus A/PR8/34-induced pulmonary inflammation
por: Krishnan, Ravi, et al.
Publicado: (2023)

Sodium pentosan polysulfate resulted in cartilage improvement in knee osteoarthritis - An open clinical trial-
por: Kumagai, Kenji, et al.
Publicado: (2010)

Efficacy of pentosan polysulfate in in vitro models of lysosomal storage disorders: Fabry and Gaucher Disease
por: Crivaro, Andrea N., et al.
Publicado: (2019)

Testosterone and the Male Skeleton: A Dual Mode of Action
por: Sinnesael, Mieke, et al.
Publicado: (2011)

Unraveling the Mode of Action of Cordyceps fumosorosea: Potential Biocontrol Agent against Plutella xylostella (Lepidoptera: Plutellidae)
por: Lei, Yanyuan, et al.
Publicado: (2021)

Physiologically Aggregated LacZ Applied in Trehalose Galactosylation in a Recycled Batch Mode
por: Belkova, Martina, et al.
Publicado: (2023)

Sordarin, an antifungal agent with a unique mode of action
por: Liang, Huan
Publicado: (2008)

Molecular Mode of Action of Asteriscus graveolens as an Anticancer Agent
por: Tayeh, Zainab, et al.
Publicado: (2018)

A Novel Member of the Trehalose Transporter Family Functions as an H(+)-Dependent Trehalose Transporter in the Reabsorption of Trehalose in Malpighian Tubules
por: Kikuta, Shingo, et al.
Publicado: (2012)

Postmortem findings in a case of variant Creutzfeldt-Jakob disease treated with intraventricular pentosan polysulfate
por: Newman, P K, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ffsdfu9c2ers4prfe2e26ukj74