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Structure and transport mechanism of the sodium/proton antiporter MjNhaP1

Sodium/proton antiporters are essential for sodium and pH homeostasis and play a major role in human health and disease. We determined the structures of the archaeal sodium/proton antiporter MjNhaP1 in two complementary states. The inward-open state was obtained by x-ray crystallography in the prese...

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Detalles Bibliográficos
Autores principales: Paulino, Cristina, Wöhlert, David, Kapotova, Ekaterina, Yildiz, Özkan, Kühlbrandt, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381896/
https://www.ncbi.nlm.nih.gov/pubmed/25426803
http://dx.doi.org/10.7554/eLife.03583